python GitHub repositories

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★ 536+1 todayPython

dipy/dipy

DIPY is the paragon 3D/4D+ medical imaging library in Python. Contains generic methods for spatial normalization, signal processing, machine learning, statistical analysis and visualization of medical images. Additionally, it contains specialized methods for computational anatomy including diffusion, perfusion and structural imaging.

perpetual-ml/perpetual

Perpetual is a high-performance gradient boosting machine. It delivers optimal accuracy in a single run without complex tuning through a simple budget parameter. It features out-of-the-box support for causal ML, continual learning, native calibration, and robust drift monitoring, along with Rust core and zero-copy bindings for Python and R

★ 715+1 todayRust

spotify/voyager

🛰️ An approximate nearest-neighbor search library for Python and Java with a focus on ease of use, simplicity, and deployability.

★ 1.6K+1 todayC++

machine-learning hacktoberfest

optuna/optuna-examples

Examples for https://github.com/optuna/optuna

★ 865+1 todayPython

om-ai-lab/OmAgent

[EMNLP-2024] Build multimodal language agents for fast prototype and production

★ 2.7K+1 todayPython

llm agent

lukasmasuch/best-of-ml-python

🏆 A ranked list of awesome machine learning Python libraries. Updated weekly.

TorchIO-project/torchio

Medical imaging processing for AI applications.

★ 2.5K+1 todayPython

griptape-ai/griptape

Modular Python framework for AI agents and workflows with chain-of-thought reasoning, tools, and memory.

★ 2.6K+1 todayPython

SolaceProducts/solace-agent-mesh

Platform for building and running AI agents across the full lifecycle — build, test, deploy, monitor, improve. Hosts your agents, runs their tools, and coordinates them over an event mesh, with sessions, artifacts, auth, evaluators, and observability built in.

★ 4.9K+1 todayShell

ai-agents python

shuxiachai/academic-commercialization-agent

AI multi-agent tool that turns research papers into cited commercialization and tech-transfer assessments: TRL, patent landscape, market and risks. CrewAI + FastAPI, with a reproducible benchmark.

huggingface/peft

🤗 PEFT: State-of-the-art Parameter-Efficient Fine-Tuning.

★ 21.9K+0 todayPython

llm pytorch

superlinked/sie

Open-source inference server and production cluster for all the models your agent needs.

zuruoke/watermark-removal

a machine learning image inpainting task that instinctively removes watermarks from image indistinguishable from the ground truth image

★ 5.2K+0 todayPython

rocketride-org/rocketride-server

High-performance AI pipeline engine with a C++ core and 50+ Python-extensible nodes. Build, debug, and scale LLM workflows with 13+ model providers, 8+ vector databases, and agent orchestration, all from your IDE. Includes VS Code extension, TypeScript/Python SDKs, and Docker deployment.

★ 17.8K+0 todayPython

ai machine-learning

promptise-com/Foundry

The foundation layer for agentic intelligence.

★ 893+0 todayPython

ai ai-agents

haris-musa/excel-mcp-server

Excel MCP server: let AI (Claude, Cursor, Codex) create and edit Excel files with charts, PivotTables, slicers and formulas. No Excel required.

★ 4.3K+0 todayPython

aibox22/readmeX

An AI Powered README and Interactive Wiki Generator for Any Projects. AI驱动的README及交互式Wiki生成工具，面向中文的开源DeepWiki。

★ 653+0 todayPython

llm cli

SwanHubX/SwanLab

⚡️SwanLab - an open-source, modern-design AI training tracking and visualization tool. Supports Cloud / Self-hosted use. Integrated with PyTorch / Transformers / verl / LLaMA Factory / ms-swift / Ultralytics / MMEngine / Keras etc.

★ 4.3K+0 todayPython

llm machine-learning

kornia/kornia

🐍 Geometric Computer Vision Library for Spatial AI

★ 11.4K+0 todayPython

ryanfrigo/kalshi-ai-trading-bot

The honest edge layer for Kalshi prediction markets - an agent-native toolkit (CLI, MCP server, Claude skill) that measures whether you actually beat the book instead of claiming it.

★ 634+0 todayPython

llm machine-learning

amitness/learning

A log of things I'm learning

★ 7.0K+0 todayUnknown

Lightning-AI/pytorch-lightning

Pretrain, finetune ANY AI model of ANY size on 1 or 10,000+ GPUs with zero code changes.

★ 31.4K+0 todayPython

ai machine-learning

agentforce314/clawcodex

Token efficient Claude Code full Python rebuild. AI Coding Agent in 310K LoC Python.

★ 924+0 todayTypeScript

NVIDIA/DALI

A GPU-accelerated library containing highly optimized building blocks and an execution engine for data processing to accelerate deep learning training and inference applications.

★ 5.8K+0 todayC++

federicodeponte/opendraft

Write research paper and literature review drafts with an open-source Python engine that checks citation DOIs against scholarly databases. Export PDF, Word, or LaTeX.

ndif-team/nnsight

The nnsight package enables interpreting and manipulating the internals of deep learned models.

★ 1.1K+0 todayPython

machine-learning pytorch

mangiucugna/json_repair

Repair malformed JSON from LLMs, APIs, logs, and user input in Python.

★ 5.1K+0 todayPython

llm cli

ucbepic/docetl

A system for agentic LLM-powered data processing and ETL

★ 4.1K+0 todayPython

llm agents

NirDiamant/Prompt_Engineering

22 prompt engineering techniques with hands-on Jupyter Notebook tutorials, from fundamental concepts to advanced strategies for leveraging LLMs.

★ 7.9K+0 todayJupyter Notebook

strands-agents/samples

Agent samples built using the Strands Agents SDK.

★ 918+0 todayPython

vstorm-co/full-stack-ai-agent-template

Full-stack AI app generator — FastAPI + Next.js with AI Agents, RAG, streaming, auth, and 20+ integrations out of the box.

★ 2.0K+0 todayPython

llm ai-agents

Trusted-AI/adversarial-robustness-toolbox

Adversarial Robustness Toolbox (ART) - Python Library for Machine Learning Security - Evasion, Poisoning, Extraction, Inference - Red and Blue Teams

★ 6.3K+0 todayPython

ai machine-learning

Annyfee/agent-craft

AI Agent 教学仓库 | 系统化 LangChain、RAG、LangGraph、MCP 全栈实战代码 | 万字博客详解 | 开源可运行示例 | 从零构建智能体

★ 524+0 todayPython

mcp rag

machine-learning data-science

biolab/orange3

🍊 :bar_chart: :bulb: Orange: Interactive data analysis

★ 5.7K+0 todayPython

Amm1rr/WebAI-to-API

Webchat to API

★ 1.4K+0 todayPython

google/grain

Library for reading and processing ML training data.

★ 799+0 todayPython

machine-learning jax

partcad/partcad

Package manager for things. Start designing modular hardware! PartCAD is the standard for documenting manufacturable physical products (a.k.a. Digital Thread or TDP). It comes with a set of tools to maintain product information and to facilitate efficient and effective workflows at all product lifecycle phases, boosted by AI.

★ 509+0 todayPython

3d cad

machine-learning hacktoberfest

Anil-matcha/open-agent-email

Open-source email infrastructure for AI agents: secure inboxes, REST and MCP APIs, SMTP, human approval workflows, signed webhooks, and Python and TypeScript SDKs. Self-host with Docker and PostgreSQL.

arc53/DocsGPT

Private AI platform for agents, assistants and enterprise search. Built-in Agent Builder, Deep research, Document analysis, Multi-model support, and API connectivity for agents.

LibrePhotos/librephotos

A self-hosted open source photo management service.

★ 8.1K+0 todayPython

mock-server/mockserver-monorepo

MockServer is an HTTP(S) mock server and proxy for testing that lets you mock APIs, inspect and modify live traffic, and inject failures. It supports HTTP/1.1, HTTP/2, gRPC, WebSockets, TCP and more on a single port, with additional support for HTTP/3, message brokers, and AI/LLM APIs.

★ 5.0K+0 todayJava

jeshraghian/snntorch

Deep and online learning with spiking neural networks in Python

★ 2.1K+0 todayPython

machine-learning pytorch

NVIDIA/kvpress

LLM KV cache compression made easy

★ 1.2K+0 todayPython

llm pytorch

tensorflow/quantum

An open-source Python framework for hybrid quantum-classical machine learning.

pyro-ppl/pyro

Deep universal probabilistic programming with Python and PyTorch

★ 9.1K+0 todayPython

ScottfreeLLC/AlphaPy

Python AutoML for Trading Systems and Sports Betting

emcie-co/parlant

Build reliable customer-facing AI agents with Parlant: an interaction control harness optimized for controlled, consistent, and predictable LLM interactions.

★ 18.3K+0 todayPython

llm ai-agents